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Cancer Prevention Trials Unit

The Cancer Prevention Trials Unit (CPTU) is uniting to prevent cancer by facilitating high quality clinical trial research and producing evidence based interventions to prevent a wide range of cancers. Its aim is to provide the necessary support to enable scientifically excellent studies, which are part of the NIHR portfolio, to be successfully completed.

The CPTU is the only trials unit in the UK with particular expertise in cancer prevention and screening and is a fully accredited UKCRC Trials Unit.

The CPTU is based within the Cancer Research UK funded Centre for Epidemiology, Mathematics and Statistics. The Centre director is Professor Jack Cuzick. Professor Peter Sasieni is deputy director of the Centre and Director of the Trials Unit.

Providing Advice, Expertise and Support

The CPTU provides the scientific, technical and computing expertise needed to support clinical trial research from conception through to completion, including an open access consultancy service covering all aspects of trial design, management and analysis. It offers investigators assistance to build on their ideas or pilot studies and provide support and advice from an expert multi-disciplinary team on the best clinical trial methodology. Expertise includes:

• Epidemiology
• Systematic literature review and meta-analysis
• Trial design and conduct
• Protocol development and case report form design
• Research costs and funding applications
• Establishing collaborative networks of investigators
• Ethics and regulatory applications
• Randomisation procedures
• Strategies for patient recruitment
• Research governance and quality assurance
• Web-based data management
• Statistical analysis and reporting
• Pharmacovigilance and monitoring
• Incorporation of health economics and quality of life measures

For further details please see the CPTU website.

If you have any queries please contact the unit at cptu@cancer.org.uk.