Research
Audit and review
Our team undertake regular reviews and audits to analyse and assess the benefits of the cystic fibrosis treatments we offer and how we are doing.
We also present any new information which may benefit the cystic fibrosis community at local, national and international respiratory and cystic fibrosis conferences.
Our recent presentations include:
National/International Presentations – Jacqui Cowlard
2002 - UK Cystic Fibrosis Clinical Nurse Specialist Meeting – International CF Transition Study Presentation
2003 - ECFC, Belfast – Transition in CF
2006 - Cystic Fibrosis Medicines Study Day – Exploring adherence in adolescents
2006 - ECFC Conference Nursing Group – Exploring adherence in adolescents
International Presentations Invited Lectures – Siobhán Carr
ECFC - Belfast 2003 – Death and Dying in CF
ECFC - Copenhagen 2006 – Ethnic minorities and CF, Room 101
KingsCollegeHospital – Regional CF Meetings
2004 – Caroline Pao (presenting) 5th Annual Regional CF Meeting 2004
2006 – Caroline Pao (presenting) – 7th Annual Regional CF Meeting
In the last three years members of our Cystic Fibrosis Team for children have presented the following posters of our research at the European and North American Cystic Fibrosis annual conferences;
Cowlard J, Carr S (2006) Exploring adolescents’ adherence to CF treatment regimes Journal of Cystic Fibrosis; Volume 5, Supplement 1, Abstract 397
Rijnbende B, Cowlard J, Carr SB (2006) The value of routinely using the 3-minute Step Test at Annual Review; Volume 5, Supplement 1, Abstract 351
Cowlard J, Carr S (2005) Are adherence issues really worse in adolescents with CF? Paediatric Pulmonology A505; Supp 28
Elston C, Butler M, Kuitert L, Carr SB (2004) Clinical features associated with an increased risk of DIOS in an adult population Pediatric Pulmonology p527, A417
Rijnbende B, Carr SB, Price E (2003) Sputum samples for microbiology – does the timing matter? Journal of Cystic Fibrosis, Volume 2, Supplement 1, Abstract 258
Cowlard J, Attard J (2003) Changes in Transition Services for Young People with CF Journal of Cystic Fibrosis (2) Abstract 267A
Van Niekerk K and Carr SB (2003) Micronutrients; Relationship with Nutrition and Disease in Children with Cystic Fibrosis J of CF, Volume 2 Abstract 338
Blakeley K. (2003) Developmental trends in children with CF. Paed Pulm Anaheim Supp
Cowlard J (2002) Transition in cystic fibrosis: not just a paediatric issue Paediatric Pulmonology A432; Supp 24
Pao CS, Prasad SA, Carr SB, Dinwiddie R, Ranganathan S. The relationship of vitamin A to lung function in children with Cystic Fibrosis. Paed Pulm Supp 24. Abstract 387
Pao CS, Wallis C. (2002) Simultaneous bilateral sweat testing- two for the price of one? ECFC
Pao CS, Dinwiddie RD. (2002) Measuring lung hyperinflation in children with Cystic Fibrosis. ECFC
Callaghan BD, Carr S, Balfour-Lynn I, Dinwiddie R (2002) Do asian CF patients have more severe disease than their caucasian peers in childhood? Paed Pulm. Page 524, A437
Research
Pharmaceutical research
We often recruit patients to clinical trials run either independently or by pharmaceutical companies investigating new drug treatments in cystic fibrosis. Dr Carr is Primary Investigator at present on a trial being run by Pharmaxis looking at inhaled Mannitol and the effect it has on the lungs in cystic fibrosis. These trials are co-ordinated through the Lung Research Centre.
Local research
Our local research programmes have included working independently and also as part of the London CF Collaboration. Research studies have included – infant lung function in CF, teenage eating disorders, urinary incontinence, adherence in adolescents, effects of ethnicity in CF, effects on growth velocity in CF related diabetes and the role of micronutrients (vitamin A, vitamin K, probiotics and antioxidants).
Publications
Lum S, Gustafsson P, Ljungberg H, Hulskamp G, Bush A, Carr SB, Castle R, Hoo AF, Price J, Ranganathan S, Stroobant J, Wade A, Wallis C, Wyatt H, Stocks J. Early detection of cystic fibrosis lung disease: multiple-breath washout versus raised volume tests. Thorax. 2007 Apr;62(4):341-7. Epub 2006 Nov 22.
Prasad SA, Balfour-Lynn IM, Carr SB, Madge SL. A comparison of the prevalence of urinary incontinence in girls with cystic fibrosis, asthma, and healthy controls. Pediatr Pulmonology 2006 Nov;41(11):1065-8.
Callaghan BD, Hoo AF, Dinwiddie R, Balfour-Lynn IM, Carr SB. Growth and lung function in Asian patients with cystic fibrosis. Arch Dis Child. 2005 Oct;90(10):1029-32.
Aurora P, Bush A, Gustafsson P, Oliver C, Wallis C, Price J, Stroobant J, Carr S, Stocks J; London Cystic Fibrosis Collaboration. Multiple-breath washout as a marker of lung disease in preschool children with cystic fibrosis.
Am J Respir Crit Care Med. 2005 Feb 1;171(3):249-56. Epub 2004 Oct 29. Ranganathan SC, Stocks J, Dezateux C, Bush A, Wade A, Carr S, Castle R, Dinwiddie R, Hoo AF, Lum S, Price J, Stroobant J, Wallis C. The evolution of airway function in early childhood following clinical diagnosis of cystic fibrosis.
Am J Respir Crit Care Med. 2004 Apr 15;169(8):928-33. Epub 2004 Jan 30. Ranganathan SC, Bush A, Dezateux C, Carr SB, Hoo AF, Lum S, Madge S, Price J, Stroobant J, Wade A, Wallis C, Wyatt H, Stocks J. Relative ability of full and partial forced expiratory manoeuvres to identify diminished airway function in infants with cystic fibrosis. Am J Respir Crit Care Med. 2002 Nov 15;166(10):1350-7.
Cowlard J (2003) CF: Transition from paediatric to adult care. Nursing Standard Oct 8-14; 39-41.
Cowlard J (2002) The role of the CF nurse specialist. Nursing Times March 21-27; 62-63.
